Haruhiko Koseki Selected Research

KDEL receptor

1/2014	Late-onset of spinal neurodegeneration in knock-in mice expressing a mutant BiP.
9/2004	Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice.

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Haruhiko Koseki Research Topics

Disease

27	Neoplasms (Cancer) 10/2020 - 03/2007
9	Inflammation (Inflammations) 01/2021 - 10/2009
6	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2020 - 05/2014
5	Dermatitis 11/2022 - 01/2016
4	Alzheimer Disease (Alzheimer's Disease) 12/2006 - 06/2003
3	Carcinogenesis 01/2022 - 02/2008
3	Infections 01/2022 - 01/2020
3	Hematologic Neoplasms (Hematological Malignancy) 12/2018 - 10/2017
2	Respiratory Insufficiency (Respiratory Failure) 11/2019 - 01/2017
2	Splenomegaly 01/2019 - 07/2002
2	Leukemia 01/2018 - 01/2014
2	Neuroblastoma 07/2017 - 07/2013
2	Insulin Resistance 01/2016 - 04/2005
2	Obesity 01/2016 - 04/2005
2	Colitis 12/2013 - 03/2003
2	Osteosarcoma (Osteogenic Sarcoma) 07/2010 - 08/2003
1	Blister (Bulla) 01/2022
1	Primary Myelofibrosis (Myelosclerosis) 01/2022
1	Pemphigus (Pemphigus Vulgaris) 01/2022
1	Cardiomegaly (Heart Hypertrophy) 01/2022
1	Myocarditis (Carditis) 01/2022
1	Hepatitis B 01/2022
1	Viremia 01/2022
1	Chronic Hepatitis B 01/2022
1	Hypoxia (Hypoxemia) 12/2021
1	Job Syndrome (Hyper-IgE Syndrome) 01/2021
1	Atopic Dermatitis (Atopic Eczema) 01/2021
1	Chronic Mucocutaneous Candidiasis 12/2020
1	Fatigue 11/2020
1	Head and Neck Neoplasms (Head and Neck Cancer) 10/2020
1	Perinatal Death 11/2019
1	Graft vs Host Disease (Graft-Versus-Host Disease) 03/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019
1	Lymphadenopathy 01/2019
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2018
1	Cardiac Arrhythmias (Arrythmia) 05/2016

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 11/2019 - 09/2004
5	ChromatinIBA 01/2020 - 08/2003
5	AntigensIBA 05/2017 - 01/2013
4	CytokinesIBA 01/2022 - 10/2009
4	Co-Repressor ProteinsIBA 10/2019 - 10/2017
4	Presenilin-1IBA 12/2006 - 06/2003
3	Histones (Histone)IBA 01/2022 - 01/2014
3	RNA Splicing FactorsIBA 01/2018 - 10/2012
3	Messenger RNA (mRNA)IBA 08/2015 - 07/2010
2	LipidsIBA 11/2022 - 04/2005
2	RNA (Ribonucleic Acid)IBA 11/2022 - 01/2018
2	Polycomb Repressive Complex 2IBA 01/2022 - 06/2014
2	Immunoglobulin G (IgG)IBA 01/2022 - 01/2022
2	Transcription Factors (Transcription Factor)IBA 01/2022 - 05/2016
2	Oxygen (Dioxygen)IBA 12/2021 - 07/2002
2	LigandsIBA 10/2020 - 12/2016
2	AntibodiesIBA 01/2020 - 08/2003
2	ZincIBA 10/2016 - 08/2014
2	KDEL receptorIBA 01/2014 - 09/2004
2	Polycomb-Group ProteinsIBA 05/2011 - 02/2008
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2022
1	Bile Acids and Salts (Bile Acids)IBA 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	Monoclonal AntibodiesIBA 01/2022
1	Amino Acids FDA Link 01/2022
1	Lysine (L-Lysine)FDA Link 01/2022
1	DesmogleinsIBA 01/2022
1	Immunoglobulin M (IgM)IBA 01/2022
1	Desmoglein 3IBA 01/2022
1	myrcludex-BIBA 01/2022
1	Interleukin-4 (Interleukin 4)IBA 01/2022
1	ChemokinesIBA 01/2022
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021
1	Interleukin-17 (Interleukin 17)IBA 01/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021
1	GlucocorticoidsIBA 01/2021
1	STAT1 Transcription FactorIBA 12/2020
1	Lipoproteins (Lipoprotein)IBA 11/2020
1	InterferonsIBA 10/2020
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2020
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 01/2020
1	CohesinsIBA 01/2020
1	DisulfidesIBA 11/2019
1	Protease Inhibitors (Protease Inhibitor)IBA 11/2019
1	anti-dsDNA autoantibodyIBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	AutoantibodiesIBA 01/2019
1	InterleukinsIBA 01/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	interleukin-22 receptor (IL-22R)IBA 01/2018
1	Interleukin-22 (IL-22)IBA 01/2018
1	Epidermal Growth Factor (EGF)IBA 07/2017
1	AgarIBA 07/2017
1	activin AIBA 07/2017
1	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2017
1	CateninsIBA 01/2016
1	AdipokinesIBA 01/2016
1	Ointments (Pastes)IBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016

Therapy/Procedure

5	Therapeutics 10/2020 - 06/2012
5	Immunotherapy 10/2020 - 06/2012
1	Stem Cell Transplantation 03/2019
1	Drug Therapy (Chemotherapy) 01/2018